ADGRF1
Function
Orphan receptor.
Post-translational modifications
Glycosylated.
Autoproteolytically processed at the GPS region of the GAIN-B domain; this cleavage modulates receptor activity.
Sequence Similarities
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Tissue Specificity
Mainly expressed in the kidney. Up-regulated in lung adenocarcinomas and prostate cancers.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
- Isoform 2
- Secreted
Alternative names
GPR110, PGR19, ADGRF1, Adhesion G-protein coupled receptor F1, G protein-coupled receptor 110, G protein-coupled receptor KPG_012, G protein-coupled receptor PGR19