ADORA2A

The cytoplasmic C-terminal domain is necessary for targeting the non-ubiquitinated form of this protein to the cell surface.

Receptor for adenosine (PubMed:2125216). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:2125216).

Ubiquitinated. Deubiquitinated by USP4; leading to stabilization and expression at the cell surface (By similarity).

Belongs to the G-protein coupled receptor 1 family.

• Cell membrane
• Multi-pass membrane protein
• Colocalizes with GAS2L2 at neuronal processes.

RDC8, Adenosine receptor A2a

• swissprot:P11617

Proteins

Immuno-oncology