ADRB3
Function
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Tissue Specificity
Expressed mainly in adipose tissues.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
ADRB3R, B3AR, ADRB3, Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor