Adss2

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.

Belongs to the adenylosuccinate synthetase family.

• Cytoplasm
• Mitochondrion
• Partially associated with particulate fractions.

ADSS, ADSS2, Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, IMP--aspartate ligase 2, L-type adenylosuccinate synthetase

• entrezGene:159
• omim:103060
• swissprot:P30520

Proteins

50097Da