AIFM3

The Rieske domain induces apoptosis.

Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.

Belongs to the FAD-dependent oxidoreductase family.

Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

• Mitochondrion
• Does not translocate to the nucleus upon induction of apoptosis.

AIFL, AIFM3, Apoptosis-inducing factor 3, Apoptosis-inducing factor-like protein

• entrezGene:150209
• swissprot:Q96NN9

Proteins

Oncology

66791Da