AIG1

Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (PubMed:27018888). Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (PubMed:27018888).

Belongs to the AIG1 family.

Highly expressed in heart, ovary, testis, liver, and kidney, at lower levels in spleen, prostate, brain, skeletal muscle, pancreas, small intestine and colon, and undetected in peripheral blood leukocytes, thymus, lung and placenta. AIG1 expression is higher in hair follicles from males than from females.

• Cell membrane
• Multi-pass membrane protein

CGI-103, AIG1, Androgen-induced gene 1 protein, AIG-1, Fatty acid esters of hydroxy fatty acids hydrolase AIG1, FAHFA hydrolase AIG1

• entrezGene:51390
• omim:608514
• swissprot:Q9NVV5

Proteins

27458Da