ALDH1B1
Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Pathway
Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
Sequence Similarities
Belongs to the aldehyde dehydrogenase family.
Tissue Specificity
Liver, testis and to a lesser extent in brain.
Cellular localization
- Mitochondrion matrix
Alternative names
ALDH5, ALDHX, ALDH1B1, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase family 1 member B1