ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
Belongs to the aldehyde dehydrogenase family.
Liver, testis and to a lesser extent in brain.
ALDH5, ALDHX, ALDH1B1, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase family 1 member B1
Proteins
57206Da
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ab246928