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ALDH3B2

Function

Oxidizes medium and long chain fatty aldehydes in lipid droplets into non-toxic fatty acids.

Pathway

Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.

Post-translational modifications

Geranylgeranylation is important for localization to lipid droplets and enzyme activity.

Sequence Similarities

Belongs to the aldehyde dehydrogenase family.

Tissue Specificity

Salivary gland (PubMed:8890755). Expressed at protein level in placenta (PubMed:31847104).

Cellular localization

Alternative names

ALDH8, ALDH3B2, Aldehyde dehydrogenase family 3 member B2, Aldehyde dehydrogenase 8, Long-chain fatty aldehyde dehydrogenase

swissprot:P48448 entrezGene:222 omim:601917