Alpha-catulin
Function
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
Sequence Similarities
Belongs to the vinculin/alpha-catenin family.
Tissue Specificity
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cell membrane
- Peripheral membrane protein
Alternative names
Alpha-catulin, Alpha-catenin-related protein, Catenin alpha-like protein 1, ACRP, CTNNAL1