AMY1A

Function

Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308). Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308).

Sequence Similarities

Belongs to the glycosyl hydrolase 13 family.

Cellular localization

• Secreted

Alternative names

AMY1, AMY1A, Alpha-amylase 1A, Salivary alpha-amylase

Database links

swissprot:P0DUB6 entrezGene:278 entrezGene:277 entrezGene:276 swissprot:P04745 omim:104702 omim:104701 omim:104700