ANKRD1
Function
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Tissue Specificity
Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.
Cellular localization
- Nucleus
Alternative names
C193, CARP, HA1A2, ANKRD1, Ankyrin repeat domain-containing protein 1, Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein