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ANXA7

Domain

A pair of annexin repeats may form one binding site for calcium and phospholipid.

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.

Sequence Similarities

Belongs to the annexin family.

Tissue Specificity

Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.

Alternative names

ANX7, SNX, OK/SW-cl.95, ANXA7, Annexin A7, Annexin VII, Annexin-7, Synexin

swissprot:P20073 entrezGene:310 omim:186360