Apob
Function
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Post-translational modifications
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
Tissue Specificity
Detected in intestine and liver (at protein level).
Cellular localization
- Cytoplasm
- Secreted
- Lipid droplet
Alternative names
Aa1064, Ac1-060, Apob, Apolipoprotein B-100, Apo B-100, Apolipoprotein B100