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APOBEC2

Function

Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Sequence Similarities

Belongs to the cytidine and deoxycytidylate deaminase family.

Tissue Specificity

Expressed exclusively in heart and skeletal muscle.

Alternative names

C->U-editing enzyme APOBEC-2, mRNA(cytosine(6666)) deaminase 2, APOBEC2

swissprot:Q9Y235 entrezGene:10930 omim:604797