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Apo-D

Function

APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.

Post-translational modifications

N-glycosylatd. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor).

Sequence similarities

Belongs to the calycin superfamily. Lipocalin family.

Tissue specificity

Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

Cellular localization

  • Secreted

Alternative names

  • Apolipoprotein D
  • Apo-D
  • ApoD
  • APOD

Target type

Proteins

Molecular weight

21276Da