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Amphiregulin
Function
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Sequence similarities
Belongs to the amphiregulin family.
Cellular localization
- Membrane
- Single-pass membrane protein
Alternative names
- Amphiregulin
- AR
- Colorectum cell-derived growth factor
- CRDGF
- AREG
- AREGB
- SDGF
Target type
Proteins
Primary research area
Oncology
Other research areas
- Immuno-oncology
Molecular weight
27895Da