Amphiregulin

Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

Belongs to the amphiregulin family.

• Membrane
• Single-pass membrane protein

AREGB, SDGF, AREG, Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF

• entrezGene:374
• entrezGene:727738
• omim:104640
• swissprot:P15514

Proteins

Oncology

• Immuno-oncology

27895Da