ARFRP1
Function
Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
Sequence Similarities
Belongs to the small GTPase superfamily. Arf family.
Tissue Specificity
Found in most tissues.
Cellular localization
- Golgi apparatus
- Golgi apparatus
- trans-Golgi network
- Located in the trans-Golgi in the GTP-bound active state.
Alternative names
ARP1, ARFRP1, ADP-ribosylation factor-related protein 1, ARF-related protein 1, ARP