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argG

Domain

The monomer is composed of two major structural domains: a nucleotide-binding domain and a catalytic/multimerization domain. Binding of ATP results in a large rigid body conformational change of the nucleotide binding domain.

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.

Sequence Similarities

Belongs to the argininosuccinate synthase family. Type 2 subfamily.

Cellular localization

Alternative names

b3172, JW3140, argG, Argininosuccinate synthase, Citrulline--aspartate ligase

swissprot:P0A6E4