ARHGAP5
Domain
The pG1 pseudoGTPase domain does not bind GTP.
Function
GTPase-activating protein for Rho family members (PubMed:8537347).
Tissue Specificity
Detected in skin fibroblasts (at protein level) (PubMed:8537347).
Cellular localization
- Cytoplasm
- Cell membrane
- Peripheral membrane protein
- Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.
Alternative names
RHOGAP5, ARHGAP5, Rho GTPase-activating protein 5, Rho-type GTPase-activating protein 5, p190-B