ARHGDIB
Function
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:7512369, PubMed:8356058). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
Sequence Similarities
Belongs to the Rho GDI family.
Tissue Specificity
Detected in bone marrow, thymus and spleen.
Cellular localization
- Cytoplasm
- Cytosol
Alternative names
GDIA2, GDID4, RAP1GN1, ARHGDIB, Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta