Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:7512369, PubMed:8356058). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
Belongs to the Rho GDI family.
Detected in bone marrow, thymus and spleen.
GDIA2, GDID4, RAP1GN1, ARHGDIB, Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta
Proteins
Oncology
22988Da
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