ARHGEF3
Function
Acts as a guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
Tissue Specificity
Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney.
Cellular localization
- Cytoplasm
Alternative names
Rho guanine nucleotide exchange factor 3, Exchange factor found in platelets and leukemic and neuronal tissues, XPLN, ARHGEF3