ARMS2
Involvement in disease
Macular degeneration, age-related, 8
ARMD8
A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.
None
Disease susceptibility is associated with variants affecting the gene represented in this entry.
Tissue Specificity
Detected in retina and placenta.
Cellular localization
- Cytoplasm
Alternative names
Age-related maculopathy susceptibility protein 2, ARMS2