ARR3
Function
May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.
Involvement in disease
Myopia 26, X-linked, female-limited
MYP26
A form of myopia, a refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. MYP26 is characterized by typical tigroid fundus changes commonly seen in early onset high myopia, and an unusual pattern of X-linked female-limited inheritance.
None
The disease may be caused by variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the arrestin family.
Tissue Specificity
Inner and outer segments, and the inner plexiform regions of the retina.
Cellular localization
- Photoreceptor inner segment
- Cell projection
- Cilium
- Photoreceptor outer segment
Alternative names
ARRX, CAR, ARR3, Arrestin-C, Cone arrestin, Retinal cone arrestin-3, X-arrestin, C-arrestin, cArr