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Arsa

Function

Hydrolyzes cerebroside sulfate.

Post-translational modifications

The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).

Sequence Similarities

Belongs to the sulfatase family.

Cellular localization

Alternative names

As2, Arsa, Arylsulfatase A, ASA, Cerebroside-sulfatase

swissprot:P50428 entrezGene:11883