ASB13

The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein modification; protein ubiquitination.

Belongs to the ankyrin SOCS box (ASB) family.

Ankyrin repeat and SOCS box protein 13, ASB-13, ASB13

• entrezGene:79754
• omim:615055
• swissprot:Q8WXK3

Proteins

Immuno-oncology

30007Da