ASB13
Domain
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Pathway
Protein modification; protein ubiquitination.
Sequence Similarities
Belongs to the ankyrin SOCS box (ASB) family.
Alternative names
Ankyrin repeat and SOCS box protein 13, ASB-13, ASB13