ATG10

E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.

Belongs to the ATG10 family.

• Cytoplasm

APG10L, PP12616, ATG10, Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-like

• entrezGene:83734
• omim:610800
• swissprot:Q9H0Y0

Proteins

Oncology

25279Da