ATMIN

Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.

Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.

• Nucleus
• Nuclear, in discrete foci during G1 phase.

KIAA0431, ZNF822, ATMIN, ATM interactor, ATM/ATR-substrate CHK2-interacting zinc finger protein, Zinc finger protein 822, ASCIZ

• entrezGene:23300
• omim:614693
• swissprot:O43313

Proteins

88348Da