B3GALT5
Function
Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor.
Pathway
Protein modification; protein glycosylation.
Sequence Similarities
Belongs to the glycosyltransferase 31 family.
Tissue Specificity
Expressed in stomach, jejunum, colon, pancreas, small intestine, testis and gastrointestinal and pancreatic cancer cell lines. Hardly detected in lung, liver, adrenal gland and peripheral blood leukocytes.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
Beta3Gal-T5, Beta3GalT5, b3Gal-T5, Beta-3-Gx-T5, B3GALT5