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B3GNT2

Function

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase.

Pathway

Protein modification; protein glycosylation.

Sequence Similarities

Belongs to the glycosyltransferase 31 family.

Tissue Specificity

Ubiquitous.

Cellular localization

Alternative names

B3GALT7, B3GNT1, B3GNT2, Beta-3-Gx-T7, BGnT-1, Beta3Gn-T1, Beta3Gal-T7, Beta3GalT7, b3Gal-T7, BGnT-2, Beta3Gn-T2

swissprot:Q9NY97 entrezGene:10678 omim:605581