B4GALT2

Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (PubMed:9405390). Can produce lactose (PubMed:9405390).

Pathway

Protein modification; protein glycosylation.

Sequence Similarities

Belongs to the glycosyltransferase 7 family.

Tissue Specificity

Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain.

Cellular localization

• Golgi apparatus
• Golgi stack membrane
• Single-pass type II membrane protein
• Trans cisternae of Golgi stack.

Alternative names

Beta4Gal-T2, b4Gal-T2, Lactose synthase A protein, N-acetyllactosamine synthase, Nal synthase, B4GALT2

Database links

swissprot:O60909 entrezGene:8704 entrezGene:8703 swissprot:O60512 omim:604013