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BAG2

Function

Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release (PubMed:24318877, PubMed:9873016).

Alternative names

BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, BAG2

swissprot:O95816 entrezGene:9532 omim:603882