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Domain

The IMD domain is predicted to have a helical structure. It may induce actin bundling and filopodia formation (By similarity).

Function

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.

Post-translational modifications

Phosphorylated on tyrosine in response to insulin.

Cellular localization

  • Cytoplasm
  • Cytoskeleton
  • Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.

Alternative names

IRTKS, BAIAP2L1, BAR/IMD domain-containing adapter protein 2-like 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate, BAI1-associated protein 2-like protein 1

Target type

Proteins

Molecular weight

56883Da

We found 2 products in 1 category

Primary Antibodies

Reactive species

Search our catalogue for 'BAIAP2L1' (2)

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