BAIAP2L1
Domain
The IMD domain is predicted to have a helical structure. It may induce actin bundling and filopodia formation (By similarity).
Function
May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.
Post-translational modifications
Phosphorylated on tyrosine in response to insulin.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.
Alternative names
IRTKS, BAIAP2L1, BAR/IMD domain-containing adapter protein 2-like 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate, BAI1-associated protein 2-like protein 1