BAMBI/NMA

Expression in poorly metastatic human melanoma cell lines; no expression in highly metastatic human melanoma cell lines.

Negatively regulates TGF-beta signaling.

Belongs to the BAMBI family.

High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.

• Membrane
• Single-pass type I membrane protein

NMA, BAMBI, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA

• entrezGene:25805
• omim:604444
• swissprot:Q13145

Proteins

Oncology

29108Da