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BARX2

Function

Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia (By similarity).

Sequence Similarities

Belongs to the BAR homeobox family.

Tissue Specificity

Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.

Cellular localization

Alternative names

Homeobox protein BarH-like 2, BARX2

swissprot:Q9UMQ3 entrezGene:8538 omim:604823