BCAT1
Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Sequence Similarities
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Tissue Specificity
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.
Cellular localization
- Cytoplasm
Alternative names
BCT1, ECA39, BCAT1, BCAT(c)