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Function

Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Sequence similarities

Belongs to the type-B carboxylesterase/lipase family.

Tissue specificity

Present in most cells except erythrocytes.

Cellular localization

  • Secreted

Alternative names

Cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase, Bche

Target type

Proteins

Primary research area

Neuroscience

Other research areas

  • Cardiovascular

Molecular weight

68462Da