Beta-1,4-galactosyltransferase 3

Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

Pathway

Protein modification; protein glycosylation.

Sequence Similarities

Belongs to the glycosyltransferase 7 family.

Tissue Specificity

Found in various tissues. Highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain.

Cellular localization

• Golgi apparatus
• Golgi stack membrane
• Single-pass type II membrane protein
• Trans cisternae of Golgi stack.

Alternative names

Beta4Gal-T3, b4Gal-T3, N-acetyllactosamine synthase, Nal synthase, B4GALT3

Database links

swissprot:O60512 omim:604014 entrezGene:8704 entrezGene:8703 entrezGene:8702 swissprot:O60513 swissprot:O60909