BFAR
Function
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
Tissue Specificity
Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen.
Cellular localization
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
Alternative names
BAR, RNF47, BFAR, Bifunctional apoptosis regulator, RING finger protein 47