BOLA1
Function
Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5 (PubMed:27532772). May protect cells against oxidative stress (PubMed:22746225).
Sequence Similarities
Belongs to the BolA/IbaG family.
Tissue Specificity
Widely expressed.
Cellular localization
- Mitochondrion
Alternative names
CGI-143, BOLA1, BolA-like protein 1, hBolA