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BRK1

Function

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Sequence Similarities

Belongs to the BRK1 family.

Cellular localization

Alternative names

C3orf10, HSPC300, MDS027, BRK1, Protein BRICK1

swissprot:Q8WUW1 entrezGene:55845 omim:611183