BTN2A2

Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

N-glycosylated.

Belongs to the immunoglobulin superfamily. BTN/MOG family.

Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.

• Membrane
• Single-pass type I membrane protein

BT2.2, BTF2, BTN2A2, Butyrophilin subfamily 2 member A2

• entrezGene:10385
• omim:613591
• swissprot:Q8WVV5

Proteins

Immuno-oncology

59070Da