BTN2A2
Function
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Tissue Specificity
Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.
Cellular localization
- Membrane
- Single-pass type I membrane protein
Alternative names
BT2.2, BTF2, BTN2A2, Butyrophilin subfamily 2 member A2