BUD31
Domain
Contains a short sequence motif (Phe-Xaa-Xaa-Phe-Tyr) that can bind to AR and may modulate AR activity.
Function
Involved in the pre-mRNA splicing process (PubMed:28076346, PubMed:28502770). May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity (PubMed:25091737).
Sequence Similarities
Belongs to the BUD31 (G10) family.
Tissue Specificity
Detected in epithelial and stromal cells in benign prostate hyperplasia tissue (at protein level).
Cellular localization
- Nucleus
- Detected in chromatin at the promoter of AR target genes.
Alternative names
EDG2, BUD31, Protein BUD31 homolog, Protein EDG-2, Protein G10 homolog