CACNB3
Function
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).
Sequence Similarities
Belongs to the calcium channel beta subunit family.
Tissue Specificity
Expressed mostly in brain, colon and ovary.
Cellular localization
- Cytoplasm
Alternative names
CACNLB3, CACNB3, Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3