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Calb1

Domain

This protein has four functional calcium-binding sites; potential sites II and VI have lost affinity for calcium.

Function

Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

Sequence Similarities

Belongs to the calbindin family.

Tissue Specificity

Expressed in the modiolar nerve root and in bushy neurons in the ventral cochlear nucleus (at protein level).

Alternative names

Calbindin, Calbindin D28, D-28K, PCD-29, Spot 35 protein, Calb1

swissprot:P12658 entrezGene:12307