Calcium-binding protein 8

The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.

Brain specific.

• Golgi apparatus
• trans-Golgi network membrane
• Single-pass type IV membrane protein
• Cytoplasm
• Perinuclear region
• Cell membrane
• Single-pass type IV membrane protein

CABP8, CALN1, Calcium-binding protein 8, CaBP8, Calneuron I, Calneuron-1

• entrezGene:83698
• omim:607176
• swissprot:Q9BXU9

Proteins

Neuroscience

29324Da