CAMK2N2
Function
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2) (PubMed:11444830). Traps Ca(2+)/calmodulin on CAMK2 (By similarity).
Sequence Similarities
Belongs to the CAMK2N family.
Tissue Specificity
Highly Expressed in keyhole limpet hemocyanin-stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC (PubMed:11444830). Highly expressed in kidney and liver (PubMed:11444830). Moderately expressed in heart, skeletal muscle, and placenta (PubMed:11444830). Weakly expressed in the small intestine (PubMed:11444830).
Cellular localization
- Nucleus
- Cytoplasm
- Cytosol
- Synapse
- Excluded from nucleus when coexpressed with activated CAMK2.
Alternative names
Calcium/calmodulin-dependent protein kinase II inhibitor 2, CaM-KII inhibitory protein, CaM-KIIN, CAMK2N2