cAMP-dependent protein kinase catalytic subunit gamma
Function
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
Involvement in disease
Bleeding disorder, platelet-type, 19
BDPLT19
A disorder characterized by increased bleeding tendency due to platelet dysfunction. Clinical features include epistaxis, hematomas, bleeding after tooth extraction, and menorrhagia.
None
The disease is caused by variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Tissue Specificity
Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
Alternative names
cAMP-dependent protein kinase catalytic subunit gamma, PKA C-gamma, PRKACG