cAMP-dependent protein kinase type II-beta regulatory subunit

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Phosphorylated by the activated catalytic chain.

Belongs to the cAMP-dependent kinase regulatory chain family.

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

• Cytoplasm
• Cell membrane
• Colocalizes with PJA2 in the cytoplasm and at the cell membrane.

cAMP-dependent protein kinase type II-beta regulatory subunit, PRKAR2B

• entrezGene:5577
• omim:176912
• swissprot:P31323

Proteins

Neuroscience

46302Da