CAPNS2
Function
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
Cellular localization
- Cytoplasm
- Cell membrane
- Translocates to the plasma membrane upon calcium binding.
Alternative names
Calpain small subunit 2, CSS2, Calcium-dependent protease small subunit 2, CAPNS2