Carboxypeptidase M
Function
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
Sequence Similarities
Belongs to the peptidase M14 family.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
Carboxypeptidase M, CPM